Effect of music selection on anxiety during intravitreal injections for individuals of varying ethnicity.
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https://doi.org/10.47513/mmd.v14i4.827##article.abstract##
Purpose: To investigate music selection as a treatment for anxiety during intravitreal injections (IVI) for individuals of varying cultures.
Methods: A randomized control study was performed to evaluate the effect of music in 3 different subject groups. 106 individuals were enrolled in the study. Individuals were randomized into one of three categories: (1) a control group in which the IVI procedure was performed without music (n=35), (2) an experimental group in which music was selected by the physician (n=36), (3) an experimental group in which music was selected by the patient (n=35). Following the procedure, all patients completed a questionnaire regarding their level of experienced anxiety, pain and discomfort (grade 0-10). The primary outcome was anxiety level during the procedure.
Results: Although no statistically significant difference in anxiety levels between groups was demonstrable, the experimental group in which patients selected music had higher number of patients with low anxiety scores compared to the other groups (p=0.04). Subjects who completed the questionnaire in Arabic were less likely to desire music on subsequent injections compare to Hebrew and English speakers (p=0.02). Music was deemed by both experimental groups as an effective method to induce relaxation (6.5±3.8 and 7.2±3.7). Preference for music on subsequent injections was increased in both experimental groups compared to the control group (P<0.01), but more prominently in the third group (P<0.01).
Conclusion: Music selection may be an effective way to reduce anxiety levels during IVI. Preference for music during IVI may be influenced by culture and previous music exposure.
##submission.citations##
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989;246:1306-1309.
Schmidt-Erfurth U, Kaiser PK, Korobelnik JF, et al. Intravitreal Aflibercept Injection for Neovascular Age-related Macular Degeneration Ninety-SixeWeek Results of the VIEW Studies. Ophthalmology. 2014;121:193-201.
Campochiaro PA, Heier JS, Feiner L, et al. Ranibizumab for Macular Edema following Branch Retinal Vein Occlusion Six-Month Primary End Point Results of a Phase III Study. OPHTHA. 2010;117:1102-1112.
Wells JA, Glassman AR, Ayala AR, et al. Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema Two-Year Results from a Comparative Effectiveness Randomized Clinical Trial. Ophthalmology. 2016;123:1351-1359.
Mclaughlin MD, Hwang JC. Trends in Vitreoretinal Procedures for Medicare Beneficiaries, 2000 to 2014. Ophthalmology. 2019;124:667-673
Lau PE, Jenkins KS, Layton CJ. Current Evidence for the Prevention of Endophthalmitis in Anti-VEGF Intravitreal Injections. J Ophthalmol. 2018;24:8567912.
Segal O, Segal-Trivitz Y, Nemet AY, Cohen P, Geffen N, Mimouni M. Anxiety levels and perceived pain intensity during intravitreal injections. Acta Ophthalmol. 2016;94:203-204.
Rifkin L, Schaal S. Factors affecting patients’ pain intensity during in office intravitreal injection procedure. Retina. 2012;32:696-700.
Miller B, Shapira Y, Flores V, Mimouni M, Shibli N, Blumenthal EZ, Zayit-Soudry S. Reducing Perceived Pain Intensity during Intravitreal Injections by Patient Handholding. Ophthalmol Retin. 2019;3:451-453.
Boyle J, Vukicevic M, Koklanis K, Itsiopoulos C, Rees G. Experiences of patients undergoing repeated intravitreal anti-vascular endothelial growth factor injections for neovascular age-related macular degeneration. Psychol Heal Med. 2018;23:127-140.
Fajnkuchen F, Delyfer M-N, Conrath J et al. Expectations and fears of patients with diabetes and macular edema treated by intravitreal injections. Acta Diabetologica. 2019;57:1081-1091.
Malakoutikhah A, Dehghan M, Ghonchehpoorc A, Afshar PP, Honarmand A. The Effect of Different Genres of Music and Silence on Relaxation and Anxiety: A Randomized Controlled Trial. Explore. 2020;1550-8307.
Richard-Lalonde M, Gélinas C, Boitor M, Gosselin E, Feeley N, Cossette S, Chlan LL. The Effect of Music on Pain in the Adult Intensive Care Unit: A Systematic Review of Randomized Controlled Trials. J Pain Symptom Manage. 2020;59:1304-1319.
Çelebi D, Yılmaz E, Tutcu S, Ahin S, Baydur H. The effect of music therapy during colonoscopy on pain, anxiety and patient comfort: A randomized controlled trial. Complementary Therapies in Clinical Practise. 2020;38:101084.
Kavak Akelma F, Altınsoy S, Arslan MT, Ergil J. Effect of favorite music on postoperative anxiety and pain. Anaesthesist. 2020;69:198-204.
Bellan L, Gooi A, Rehsia S. The Misericordia Health Centre cataract comfort study. Can J Ophthalmol. 2002;37:155-160.
Chen X, Seth RK, Rao VS, Huang JJ, Adelman RA. Effects of music therapy on intravitreal injections: A randomized clinical trial. J Ocul Pharmacol Ther. 2012;28:414-419.
Gomez J, Koozekanani DD, Feng AZ et al. Strategies for Improving Patient Comfort During Intravitreal Injections: Results from a Survey-Based Study. Ophthalmol Ther. 2016; 5:183-190.
Abend R, Dan O, Maoz K, Raz S, Bar-Haim Y. Reliability, validity and sensitivity of a computerized visual analog scale measuring state anxiety. J. Behav. Ther. & Exp. Psychiat. 2014;45:447-453. http://dx.doi.org/10.1016/j.jbtep.2014.06.004.
Fu VX, Oomens P, Sneiders D, Vandenberg S A.A, Feelders RA, Wijnhoven B P.L, Jeekel J. The Effect of Perioperative Music on the Stress Response to Surgery: A Meta-analysis. Journal of surgical research. 2019;244:444-455.
Stefano GB, Zhu W, Cadet P, Salamon E, Mantione KJ. Music alters constitutively expressed opiate and cytokine processes in listeners. Medical Science Monitor. 2004;10:18-27.
Ugras GA, Yıldırım G, Yüksel S, Ozturkcu Y, Kuzdere M, Oztekin SD. The effect of different types of music on patients’ preoperative anxiety: A randomized controlled trial. Complementary Therapies in Clinical Practice. 2018;31:158-163.
Kupeli I, Gulnahar Y. Comparing different music genres in decreasing dental anxiety in young adults who underwent third molar surgery in Turkey. J Oral Maxillofac Surg. 2020;78:546e1-546e7.
Kushnir J, Friedman A, Ehrenfeld M, Kushnir T. Coping with Preoperative Anxiety in Cesarean Section: Physiological, Cognitive, and Emotional Effects of Listening to Favorite Music. Birth. 2012;39:121-127.
Luis M, Doss R, Zayed B, Yacoub M. Effect of live oud music on physiological and psychological parameters in patients undergoing cardiac surgery. Global Cardiology Science and Practice.2019;17. https://doi.org/10.21542/gcsp.2019.17
Kayikcioglu O, Bilgin S, Seymenoglu, G, Deveci A. State and Trait Anxiety Scores of Patients Receiving Intravitreal Injections. Biomed Hub. 2017;2:478993.
Martel A, Nahon-Esteve S, Martini K, Almairac F, Baillif S. Feelings, preoperative anxiety, and need for information in patients undergoing intravitreal injections. Graefe’s Arch Clin Exp Ophthalmol. 2020;258:1395-1403.
