A web app based-music intervention (MUSIC-CARE) reduces sedative requirement and anxiety during coronary angioplasty


  • Gilles BOCCARA Department of Anesthesia and Intensive Care Medicine American Hospital of Paris, Neuilly S/Seine http://orcid.org/0000-0002-6095-8021
  • Aurelien MAZERAUD Department of Anesthesia in Sainte-Anne Hospital, Medical University of Paris-Descartes, Paris
  • David CASSAGNOL Department of Anesthesia in Presbyterian Hospital of New-York, New-York
  • François TARRAGANO Interventional Cardiology Unit, American Hospital of Paris, Neuilly S/Seine




Coronary angiography, music intervention, smartphone application, pain, drug consumption


Coronary angiography is a procedure in which patients tend to present with a moderately high level of stress and anxiety. The present investigation sought to examine the impact of a patient controlled music listening intervention by mobile application (Music-Care) on sedative consumption as primary endpoint, and on pain, anxiety and satisfaction levels. This is a prospective non-randomized controlled clinical study. Patients scheduled to undergo coronary angioplasty under local anesthesia and sedation were recruited. A 76 patients were included, 54 were assigned under the music arm and 22 under the control arm. Medication intake during the procedure has been reported as well as anxiety as measured by numeric rating score and APAIS, pain and satisfaction scores. Music group was administered "U" sequence during the procedure. Patients under music took significantly less midazolam medication (median 1 vs 3 mg in control, p<0.01). Additionally, there was a significant difference (p<0.01) on anxiety (Mmusic = 2.9, Mcontrol = 4.2, p <0.01) but not in pain score. Almost all of the patients from the music group (98%) were satisfied (score ≥ 4) vs 91% in control group. Music-Care program application provides a 2/3 reduction in midazolam sedation during coronary angiography under local anesthesia and sedation. Furthermore, cardiologists appreciated this technique and suggested it to assist with their procedure in ambulatory practice.


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