Neonatal Music Therapy and Cerebral Oxygenation in Extremely and Very Preterm Infants: a Pilot Study

Autori

  • Nienke H. van Dokkum Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen
  • Elisabeth M.W. Kooi Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen
  • Besrat Berhane Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen
  • Anne-Greet Ravensbergen Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen
  • Laurien Hakvoort ArtEZ University of the Arts Enschede
  • Artur C. Jaschke Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen
  • Arend F. Bos Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

DOI:

https://doi.org/10.47513/mmd.v13i2.813

Abstract

Music therapy is a novel intervention that may minimize neonatal stress. The mechanism of action is still largely unknown. We hypothesized that one mechanism of action regards altered brain oxygenation (either due to altered cerebral perfusion or altered cerebral oxygen consumption). We measured cerebral oxygenation before, during and after music therapy sessions using Near-Infrared Spectroscopy (NIRS). We extracted data on cerebral oxygen saturation (rcSO2) and calculated cerebral fractional tissue oxygen extraction (cFTOE). In addition, we measured heart rate. We included 20 infants, receiving 44 music therapy sessions. Median gestational age was 27 weeks, the majority were males. We identified two distinct reactions: in one group rcSO2 increased and cFTOE decreased during therapy compared with before therapy, whereas in the other group rcSO2 decreased and cFTOE increased during therapy compared with before therapy. The first may indicate a sedative effect, whereas the second may reflect a hyperalert state. The observed changes in heart rate may contribute to these observations through altered cerebral perfusion. The clinical significance of these two distinct reactions for music processing and (future) neurological functioning in these infants warrants further investigation.

Biografie autore

Nienke H. van Dokkum, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Division of Neonatology

Elisabeth M.W. Kooi, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Division of Neonatology

Besrat Berhane, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Divison of Neonatology

Anne-Greet Ravensbergen, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Division of Neonatology

Laurien Hakvoort, ArtEZ University of the Arts Enschede

Department of Music Therapy

Artur C. Jaschke, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Division of Neonatology

Arend F. Bos, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen

Department of Pediatrics, Division of Neonatology

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Pubblicato

2021-04-23

Fascicolo

V. 13 N. 2 (2021)

Sezione

Full Length Articles