Can Rhythmic Sensory Stimulation Decrease Cognitive Decline in Alzheimer's Disease?: A Clinical Case Study

Amy Clements-Cortes, Lee Bartel, Heidi Ahonen, Morris Freedman, Michael Evans, David Tang-Wai

Abstract


Background/Objectives: To present Rhythmic Sensory Stimulation (RSS) as a potential new treatment of Alzheimer’s disease (AD).

Design: Longitudinal case study over a three year period.

Setting: RSS was provided both in a long-term care/research facility and in-home.

Participant:  One 92 year old female with AD.

Intervention: Treatments consisted of RSS resulting in gamma frequency entrainment, provided by two different treatment devices over three years.

Measurements: Quantitative and qualitative measures were used including: MMSE, SLUMS, interviews, observation notes and a participant question sheet.

Results: MMSE scores since diagnosis three years earlier, as well as cognition, clarity, and awareness were reported by the case’s husband to have remained unchanged.

Conclusion: Although further research is warranted, this case suggests that RSS has potential to help maintain cognition in AD. 


Full Text:

 Subscribers Only

References


Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician. J Psychiat Res. 1975; 12(3): 189-98.

Iaccarino HF, Singer AC, Martorell AJ, et al. Gamma frequency entrainment attenuates amyloid load and modifies microglia. Nature. 2016; 540: 230-251. doi:10.1038/nature20587.

Llinas R, Urbano FJ, Leznik E, et al. Rhythmic and dysrhythmic thalamocortical dynamics: GABA systems and the edge effect. Trends Neurosci. 2005; 28(6): 325-33.

Llinás R, Ribary U, Jeanmonod D, et al. Thalamocortical dysrhythmia I: Functional and imaging aspects. Thalamus Relat Syst. 2001; 3(1): 237–44.

Llinnás R, Ribary U. Coherent 40-Hz oscillation characterizes dream state in humans. Proc Natl Acad Sci USA. 1993; 90(5): 2078-81.

Ribary U, Ionannides AA, Signh KD, et al. Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans. Proc Natl Acad Sci USA. 1991; 88(24): 11037-41.

Next Wave Headquarters. Next Wave Physioacoustic MX therapy chair. [Next Wave Headquarters web site]. Available at: http://www.nextwaveworldwide.com/products/physioacoustic-mx-therapy-chair/. Accessed May 22, 2015.

Tariq SH, Tumosa N, Chibnall JT, et al. The Saint Louis University mental status (SLUMS) examination for detecting mild cognitive impairment and dementia is more sensitive than the mini-mental status examination (MMSE) – A pilot study. Am J Geriatr Psych. 2006 14(11): 900-10.

Sound Oasis.Vibroacoustic Therapy Systems. [Headwaters Inc. web site]. Available at: http://www.soundoasis.com/product-category/vibroacoustic-therapy-systems/. Accessed November 7, 2016.

Clements-Cortes A, Ahonen H, Evan M, et al. Short term effects of rhythmic sensory stimulation in Alzheimer’s disease: An exploratory pilot study. J Alzheimers Dis.

; 52(2): 651-60. doi:10.3233/JAD-160081


Refbacks

  • There are currently no refbacks.


by The International Association for Music & Medicine